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Dianxu Ren, MD, PhD

Department: Health and Community Systems
Location: 360 Victoria Building
Email: dir8@pitt.edu
Phone: 412-624-4141

Keywords:

  • Brain Injury

Current Funded Research:

Ren, D
9/1/2007—-8/31/2009

CIRCL

Exploring the Relationship Between Functional Status and Quality of Life After Traumatic Brain Injury (TBI)

Traumatic brain injury (TBI) results in the disturbance of cognitive, behavioral, emotional, and physical functioning that leads to functional deficits (impairments), disability, and decreases in quality of life. The investigations of functional status and Quality of life (QoL) after TBI have been widely studied. However, there are very few studies to date have sought to determine the relationship between objective functional status evaluations and subjective QoL measures in individuals after TBI and the influence of potential factors on their relationship. This proposal aims to determine the relationship between functional status and QoL after TBI and explore some possible mediator/moderator effects between them using standard methods as well as structural equations modeling (SEM). This prospective study will use longitudinal data collected from patient questionnaires and from medical records of patients with moderate and severe TBI. In addition to demographic and injury related data, the functional outcomes and Quality of life of patient have been collected at 6 month and 12 month. The research set forth in this proposal capitalizes on the CDC missions “to promote health and quality of life by preventing and controlling disease, injury, and disability” and CDC research injury agenda on Acute care, disability, and rehabilitation “to investigate the long-term effects of TBI on the health and longevity of people with disability from these injuries”. And it will have a significant impact on the lives of individuals with TBI by generating new knowledge needed to improve QoL that may lead to additional interventions such as counseling, therapy, and medication changes to enhance QoL.


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Updated: March 23, 2009